Contribution of Bone marrow mesenchymal stem cells to neural stem cells protecting PC12 cells from apoptosis
نویسندگان
چکیده
The apoptosis of pheochromocytoma cells line 12 (PC12 cells) induced by serum deprivation is similar to that of dopaminergic neuron cells in Parkinson’s disease and neural stem cells (NSCs) could protect such PC12 cells from further apoptosis. Additionally, bone marrow mesenchymal stem cells (BMSCs) can improve the endogenous NSCs capacity of differentiating into oligodendrocytes which play an important role in providing local trophic support for neurons in the CNS [1,
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